Grant: $294,145 - National Institutes of Health - May. 21, 2009
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Award Description: The Principal Investigator will study DUE-B protein, how it affects the timing of replication and binding of proteins, and the link between DUE-B overexpression and ovarian cancer.
Project Description: The project will study the DNA unwinding element binding protein DUE-B, with the goal of determining the mechanism by which the binding of DUE-B to replication origins is controlled, and by which DUE-B regulates the binding of other replication initiation proteins to origins during unperturbed replication and following replication stress. The project will also characterize the effects of targeted structural mutations in DUE-B on its binding to protein ligands and its activation of replication origins.
Jobs Summary: Professor of Biochemistry; Research Assistant Professor, Biochemistry and Molecular Biology,; Technician/Research Associate; 2 Postdoctoral Fellows; 3 undergraduate students (Total jobs reported: 3)
Project Status: Less Than 50% Completed
This award's data was last updated on May. 21, 2009. Help expand these official descriptions using the wiki below.