Grant: $480,981 - National Institutes of Health - Sep. 30, 2009
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Award Description: In collaboration with scienteists at the Unversity of Texas MD Anderson Cancer Center, we will test our immunotherapeutic approach to treating HPV related cancers in a non-human primate model. This study fulfills the premises of the Grand Opportunity Grant by developing safe and potent immunotherapeutic vacines againast HIV-related maliganacies.
Project Description: Aim 1: Engineering , expression , purification and in vitro validation of vaccines; Aim 2: Testing Immunogenicity of vaccines in Rhesus macaques; Aim 3 Selection of a vaccine adjuvant in Rhesus macaques
Jobs Summary: (1) .50 FTE PhD research associate will undertake the construction of the DC - targeting expression vectors. (2) .50FTE bachelor's degree level research assistant will work under Co-Investigator to undertake the required FACS and cell biology analyses to study the binding and activation. (3 & 4) .10 FTE for two lead scientists will help preserve their positions as they lead the project to build expression cell lines secreting the vaccinesclones with antigens linked to recombinant anti-DC monoclonal antibodies.. (Total jobs reported: 0)
Project Status: Not Started
This award's data was last updated on Sep. 30, 2009. Help expand these official descriptions using the wiki below.
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|UNIVERSITY OF TEXAS M.D. ANDERSON CANCER CENTER, THE||$447,163||HOUSTON||TX|