LOS ANGELES, CA

University of California, Los Angeles

Grant: $1,864,353 - National Institutes of Health - Sep. 29, 2009

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Award Description: We propose to develop sustainable statewide infrastructure for Comparative Effectiveness Research on primary and secondary prevention of cardiovascular disease (CVD) among managed care populations. The project builds on the 'Right Care Initiative (RCI)—an existing public-private, multidisciplinary collaboration of health plans, provider groups, public health authorities, and other key stakeholders. RCI was established to address poor performance in clinical outcomes of chronic conditions, including CVD. Now in its second year, health plans and other entities that are part of RCI are sharing and pooling data and reviewing promising practices to identify opportunities for interventions to improve outcomes at local and regional levels. Although RCI is off to a promising start, it lacks the organizational and technical infrastructure necessary to effectively design, implement, and evaluate the range of multisite, multilevel interventions being considered. The Go Grant will allow us to implement this infrastructure, initiate studies, and obtain additional funding for a sustainable public-private partnership that may result in improved health outcomes in our communities. The Go Grant would allow us to rapidly implement the infrastructure RCI needs to initiate studies and obtain additional funding on an ongoing basis. Specifically, we propose to establish a research center—called the California Comparative Effectiveness and Outcomes Improvement (CEOI)—that would be designed to support the goals of the RCI while also significantly increasing the available evidence base on the comparative effectiveness of different strategies for improving the primary and secondary prevention of cardiovascular disease. Because of the size and scale of the RCI healthcare networks that will be involved in center research projects, practices that prove to be effective are likely to be widely disseminated and to have a significant impact on population health far more quickly than usual. While the CEOI will initially be designed to support efforts of the RCI and will focus on preventing cardiovascular disease (CVD), we expect it will gradually expand its scope and capacity to support comparative effectiveness studies involving entities that are not formally part of the RCI and to include care for health conditions besides CVD.

Project Description: The two years of GO funding can redress this situation by enabling us to rapidly implement the infrastructure to allow RCI participants to begin conducting rigorous comparative effectiveness studies. That infrastructure will take the form of a center—the California Comparative Effectiveness and Outcomes Improvement (CEOI) Center—and will be achieved by accomplishing the following specific aims: • Specific Aim 1: To implement infrastructure and formalize policies to enable the RCI to conduct comparative effectiveness research in California managed care organizations and their affiliated physician networks. • Specific Aim 2: To create uniform data elements that characterize process and outcomes for managed care patients with high blood pressure, high cholesterol, or high blood sugar and make such data elements accessible for comparative effectiveness research. • Specific Aim 3: Using the infrastructure and common database (Aims 1 and 2), to conduct and evaluate at least one demonstration study and apply for or secure funding for at least three more. To achieve these initial aims during the two-year funding period, we have assembled a team with complementary skills and capacities needed to establish and operate the CEOI center, including the University of California, Los Angeles; the University of California, San Diego; the RAND Corporation; and Lumetra, a health care consulting firm specializing in provider practice redesign. In addition, the RCI includes active collaboration with the State of California Department of Managed Health Care, the University of California, Berkeley, and most of the major health plans in the State of California (i.e., Blue Cross-Blue Shield, HealhtNet, Kaiser Permanente, and many others). Many provider groups throughout the state and pharmaceutical companies are also active in the collaboration.

Jobs Summary: N/A (Total jobs reported: 0)

Project Status: Not Started

This award's data was last updated on Sep. 29, 2009. Help expand these official descriptions using the wiki below.


Funds Recipient

University of California, Los Angeles
LOS ANGELES, CA 90095
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Place of Performance

Los Angeles, CA 90095
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