UNIVERSITY OF FLORIDA
Grant: $8,538 - National Institutes of Health - Jul. 13, 2009
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Award Description: This award is for a summer student supplement. I recruited one undergraduate student this summer, Michael H. Rosenberg, who is working on the specific aims outlined in the proposal. The purpose of this award is to provide training in molecular genetics to one undergraduate student. The student is expected to learn basic molecular techniques and to develop skills allowing him/her to independently conduct research. The student will participate and present in laboratory meetings in which current research projects are discussed among members of the laboratory. The focus of the student's work in the laboratory is to analyze the function of two transcription factors involved in the regulation of the beta globin genes. These transcription factors are USF and NF-E2. Preliminary data suggest that these proteins interact with each other and collaborate in the regulation of the globin genes. In addition, the student will analyze proteins recruited to the locus control region, a powerful DNA regulatory element regulating high-level expression of the beta globin genes.
Project Description: The goals of this project are to understand the function of transcription factors USF and NF-E2 in the regulation of the beta globin genes. The undergraduate student will analyze interactions between these two proteins and will also identify novel proteins that associate with the locus control region, a DNA regulatory element required for high level globin gene expression. Michael already made sustantial contributions to the research effort and helped elucidate the role of USF in globin gene regulation. He is a co-author on a recent publication from our laboratory (Liang et al., Molecular and Cellular Biology, 2009). Michael continues to work in the laboratory for research credits during the semester and will continue his funded research next summer (2010). Michael is a very enthusiatic and gifted young student. I truly appreciate the funding I received from the NIH to support his training in my laboratory.
Infrastructure Description: not applicable
Jobs Summary: The summer student supplement award provided funding for one undergraduate student for one year. This award started August 1st, 2009 and will be active until July 31, 2010. I hired one undergrdaduate student, Michael H. Rosenberg, who is conducting experiments addressing the goals outlined in the application. (Total jobs reported: 1)
Project Status: Less Than 50% Completed
This award's data was last updated on Jul. 13, 2009. Help expand these official descriptions using the wiki below.
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