Grant: $369,275 - National Institutes of Health - Sep. 9, 2009
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Award Description: 1. One of the objectives of this study is to compare the gene expression profiling data between cases studied using a set of proprietary reagents with commercially available Affymetrix reagents. The goal is to translate the data obtained from the proprietary reagent to a platform that is generally available. Another objective is to develop a robust gene expression profiling assay using formalin fixed paraffin embedded (FFPE) tissue so that rare cases can be studied as FFPE tissues are much more abundantly available. This supplement also requests money to buy a semi high throughput quantitative RT-PCR system to facilitate experiments aiming at converting gene expression profiling defined signatures into a RT-PCR platform that can be applied to FFPE tissues. The proposed studies will allow us to convert the information generated using proprietary reagents into diagnostic and prognostic signatures that can be obtained using commonly available reagents and diagnostic platforms. The extension of GEP technology to FFPE tissues will allow us to study rare tumors to generate comprehensive diagnostic signatures. It will also facilitate the utilization of gene expression profiling defined signatures generated under the SPECS initiative in routine clinical practice.
Project Description: project not yet started
Jobs Summary: none created yet (Total jobs reported: 0)
Project Status: Less Than 50% Completed
This award's data was last updated on Sep. 9, 2009. Help expand these official descriptions using the wiki below.