Grant: $238,978 - National Institutes of Health - Sep. 30, 2009
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Award Description: The focus of this research is to study the intracellular trafficking during visual system development in Drosophila. Our goal is to identify and characterize intracellular trafficking compartments and pathways that instruct synaptic specificity.
Project Description: Intracellular vesicle trafficking that is regulated by Rab GTPases is fundamental to most aspects of cellular development and function; its disruption can cause severe diseases, e.g. Griscelli syndrome, Charcot-Marie-Tooth type 2B disease, Warbug Micro Syndrome, X-linked mental retardation, Bardet-Biedl, syndrome and progressive retinal degeneration (choroideraemia). The potential of Drosophila as a genetic model system will be exploited by tagging all Rabs involved in visual system development using a new knock-in technique.
Jobs Summary: N/A (Total jobs reported: 0)
Project Status: Not Started
This award's data was last updated on Sep. 30, 2009. Help expand these official descriptions using the wiki below.