CHILDREN'S HOSPITAL MEDICAL CENTER
Grant: $12,600 - National Institutes of Health - May. 30, 2009
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Award Description: Adminstrative Supplement Notice for Students and Science Education under the Recovery Act (NOT-OD-09-060)
Project Description: The overall goals of this summer project were to 1) select and provide a motivated undergraduate student with an excellent research foundation for making career choices in health related sciences, 2) expedite accomplishment of the goals in the parent grant by identifying signaling pathways mediating Rb family control of lung epithelial regulation. Ashley Miller, a sophomore undergraduate student at University of North Carolina-Chapel Hill, was chosen from the over 850 applicants applying to the Summer Undergraduate Research Fellowship (SURF) Program. We identified p53 as a potential effector of Rb dependent lung phenotypes. The goal of Ashley’s 9 week project was to determine the effects of p53 loss and mutant expression Rb deficient lungs. Resultant conclusions were that 1) mutant p53 expression in Rb deficient lungs results in decreased survival, and 2) apoptosis in Rb deficient lungs is mediated through p53 independent mechanisms. Student Statement: 'Knowledge/Skills Acquired: The 2009 Summer Research Experience has helped me to learn more about basic cancer biology. Prior to this summer, I had no experience in immunohistochemistry, DNA isolation, or animal research. I am thankful that I now have a comprehensive understanding of research methods and have been able to experience a ‘career’ in biomedical research. Impact on Career Goals: I had always thought that medicine would be the most logical career option for someone like me who enjoys science and also desires interaction and collaboration with others. Participating in SURF this summer has really opened my eyes to another career option that combines these two aspects. I was able to see first hand the amount of collaboration and teamwork that occurs while performing biomedical research. I am now very much considering applying to an M.D. /Ph.D. combined degree program based on my experience this summer in Kathryn Wikenheiser-Brokamp’s lab .
Jobs Summary: none (Total jobs reported: 0)
Project Status: Not Started
This award's data was last updated on May. 30, 2009. Help expand these official descriptions using the wiki below.
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