Grant: $146,261 - National Science Foundation - Aug. 31, 2009
33% voted satisfied - 67% voted not satisfied - 6 vote(s) cast
Award Description: Objectives: The objective of this research is to use single-molecule techniques of atomic force (single-molecule antibody recognition force microscopy) and fluorescence microscopy/spectroscopy (time-resolved fluorescence anisotropy and fluorescence resonance energy transfer) to determine the molecular mechanism for the biomineralization of nano-magnetite (Fe3O4) crystals in magnetotactic bacteria. We propose to identify the function(s) of the individual protein molecules involved in the biomineralization process and determine how they control crystal nucleation, growth and morphology, examine the organization of the protein molecules within a bacterial membrane and with respect to nascent Fe3O4 nanoparticles, identify the amino acid sequences within these molecules required for crystal nucleation and growth, and uncover functional protein complexes required for Fe3O4 biomineralization. Expected outcomes: We expect to identify functions of specific magnetosome membrane proteins.
Project Description: Not Started
Jobs Summary: None (Total jobs reported: 0)
Project Status: Not Started
This award's data was last updated on Aug. 31, 2009. Help expand these official descriptions using the wiki below.