Grant: $384,805 - National Institutes of Health - Sep. 30, 2009
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Award Description: The origins of human diseases, such as cancer, can be generally attributed to loss-of-function of important genes (tumor suppressor genes) and/or gain-of-function of pathological genes (oncogenes). We are interested in understanding how animal cells use small RNAs to silence target gene expression. Our studies will not only advance understanding of the critical roles of small RNAs in biology and disease, but also facilitate development of novel therapeutics for human disease by using small RNAs to specifically shut down the expression of pathological genes.
Project Description: This proposed project will advance NINDS’ mission of developing new standardized tests as part of the NIH Blueprint for neuroscience, particularly quality of life and neurocognitive measures, in patients with Parkinson’s disease and comorbid depression. Further, this project will address the American Recovery and Reinvestment Act goals of 1) infrastructure investment - through conducting multidisciplinary research to create a synergistic psychometric test development platform for present and future endeavors, and 2) job preservation and creation - by employing current faculty, early career investigators and hiring new research personnel and postdoctoral scholars. This project is efficiently designed to be completed, inclusive of statistical analyses, within a two-year time frame.
Jobs Summary: N/A (Total jobs reported: 0)
Project Status: Not Started
This award's data was last updated on Sep. 30, 2009. Help expand these official descriptions using the wiki below.