RFCUNY - LEHMAN COLLEGE
Grant: $328,717 - National Institutes of Health - Sep. 8, 2009
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Award Description: Individual investigator-initiated research projects aimed at developing researchers at minority-serving institutions (MSIs) to a stage where they can transition successfully to other s extramural support (R01 or equivalent).
Project Description: Vitamin A deficiency is a global health problem associated with consumption of food crops that are poor sources of provitamin A carotenoids. This deficiency results in an immense disease burden and increased mortality in hundreds of millions of children. Alleviation of this serious economic and health problem requires a comprehensive understanding of how carotenoids are synthesized and accumulated in plants. With this knowledge, only then can the tools of molecular biology, genetics, and biochemistry be applied to improve provitamin A content in food crops in a predictable fashion. This Administrative Supplement will have the following goals to expand the research scope, accelerate research discovery, and to stimulate the economy: 1)To add to the scope of the parent grant by adding a new set of research aims to investigate a previously unknown gene/enzyme that is required for carotenoid biosynthesis in all higher plants and essential for provitamin A biofortification of maize endosperm; 2)To hire and/or retain staff (research associate and research assistant) needed to carry out the additional research scope of the Administrative Supplement and to accelerate new scientific discoveries needed to solve a major health problem.
Project Status: Less Than 50% Completed
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