PALO ALTO INSTITUTE FOR RESEARCH AND EDUCATION, INC.
Grant: $58,013 - National Institutes of Health - Jun. 5, 2009
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Award Description: This American Recovery and Reinvestment Act Administrative Summer Research Supplement proposes to increase the tempo of research activity in the associated R01 grant (R01 HL082662, An Autoimmune Basis for Pulmonary Hypertension) by hiring a Science Educator. Work outlined in this proposal will speed the generation of antibodies in sufficient quantity to deplete lymphocyte subsets as outlined in Specific Aim 3 of the R01. This Aim addresses whether immunologically normal rats can be rendered susceptible to pulmonary hypertension through depletion of lymphocyte subsets. Eleven commercially-unavailable mouse hybridomas which secrete monoclonal antibodies specific for rat inflammatory cells have been gifted to this laboratory. These hybridomas now require expansion in vitro, growth in ascites and quantification by enzyme-linked immunosorbent assay. This project is designed to provide an academically rewarding experience in biomedical research which can be completed over two summer periods. While remaining within the scope of the parent project, which characterizes inflammation in experimental pulmonary hypertension, it also provides new and powerful diagnostic and therapeutic tools which will strengthen current research efforts.
Project Description: As defined in the Award Description field.
Jobs Summary: One job was created for a high school science teacher. (Total jobs reported: 1)
Project Status: More than 50% Completed
This award's data was last updated on Jun. 5, 2009. Help expand these official descriptions using the wiki below.
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