Grant: $52,308 - National Institutes of Health - Sep. 5, 2009
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Award Description: The proposed supplement to the ongoing study of chilhood asthma is designed to accelerate the rate of recruitment of study subjects. Parents will be administered a standardized asthma questionnaire (ISAAC) to determine presence and frequency of asthma symtpoms. Exposures will be characterized both qualitatively and quantitatively, to validate the robotic sampler's estimation of exposure to particulate matter for the boys and girls ages 6-36 months, an age group when asthma is often first diagnosed. The study will employ a fourth generation of the Pre-Toddler Inhalable Particulate Environmental Robotic (PIPER) Sampler that has been developed and undergone testing as part of the parent study. A total of 200 households with children in the target age group will be enrolled. Sampling will be carried out with both a fixed height stationary sampling station, where inlets of all instruments will be at 1.1 m height, and the PIPER sampler, where inlets of all instruments will be varied based upon the age and gender specific programmed activity patterns . Four parameters will be for each household: 1) mass concentration of particles measured by a real-time monitoring device; 2) real-time particle size and number distribution (0.3->10 ?m); 3) air sampling on filters for detailed characterization of the PM constituents (pesticides, allergens, and endotoxins); 4) concentration and composition of airborne fungi (viable and non-viable) collected on glass slides. Measurements will be collected in tandem for each of the 4 types of monitoring.The results of the laboratory analysis for endotoxins, molds and allergens for cockroaches (Bla g ½), dust mites (Der f 1/p 1), dog (Can f 1), cat (Fel d 1) and mouse (Mus m1) will be evaluated for association with reporting of asthma symptoms If successful this study will provide an alternative to personal monitoring for a variety of environmental exposures that may be experienced by children too young to be assessed by conventional methods. In addition, it will open up an avenue for more precise estimation of early childhood exposures to asthmagens in the PM aerosols.
Project Description: Not Started
Jobs Summary: Student Worker: Provides technical support for operation of sampling robot for field work. (Total jobs reported: 0)
Project Status: Less Than 50% Completed
This award's data was last updated on Sep. 5, 2009. Help expand these official descriptions using the wiki below.