Grant: $315,634 - National Institutes of Health - Jul. 21, 2009
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Award Description: Activity of synthetic phorbol esters on latent HIV
Project Description: We have requested this supplement to provide an opportunity to rapidly accelerate identification of compounds with potential clinical utility in activation/elimination therapeutic strategies to target latent HIV. It has previously been shown that prostratin, a naturally ocurring phorbol ester, can activate latent HIV. We will test in in vitro latency models how chemically sythesized derivatives of prostratin act on latently infected cells, to determine if a molecule with improved properties can be found.
Jobs Summary: UCLA is a world-class educational institution in the midst of an unprecedented financial crisis that threatens our mission to provide education, research and public service benefiting millions of people. ARRA funding to the University has enabled the creation and retention of jobs to support vital scientific research and training activities that would otherwise be severely constrained or eliminated through budget cuts. The type(s) of jobs created and retained by this ARRA-fund award includes: Scientific/Technical Professionals and Staff positions, such as Researchers, Post-Docs, Graduate Student Researchers, Project Managers and Statisticians. (Total jobs reported: 1)
Project Status: Less Than 50% Completed
This award's data was last updated on Jul. 21, 2009. Help expand these official descriptions using the wiki below.