GEORGE MASON UNIVERSITY
Grant: $10,805 - National Institutes of Health - Jun. 4, 2009
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Award Description: Parent R21 Grant: Surrogate and Sentinal Technologies to Monitor Stability of Cancer Phosphoproteins The purpose of this ARRA supplement is to provide paid short-term research internship experience to high school and/or college students that are considering health-related science careers, with the intent to encourage their scientific career goals while accelerating research performed under the parent R21 grant. The ARRA supplement is used to provide salary and supplies for these summer interns. The students analyze various permutations of stabilizing chemistries to optimize room temperature preservation of nucleic acids and proteins. Data produced by the student interns allows the GMU team, including the students, to develop nanoparticle sentinels that record tissue phosphoprotein preservation during processing and molecular analysis, and provide choice candidate phosphopeptides that provide the most labile phosphoendpoints for quality control/quality assurance monitoring.
Project Description: The aim of this supplement application is to encourage students who express interest in the medical field to pursue an advanced degree such as a PhD or MD by exposing them to a hospital setting and clinical surgical procedures, while providing the interns with a supervised, medically relevant research project. The students interact with pathologists and clinical research coordinators as well as GMU researchers. Summer student interns perform tissue staining and laser capture microdissection at GMU, and are trained in the latest proteomic microarray technology developed in the PI’s lab and employed in the parent study. Together with their mentor, the students determine the types of fixatives, additives, and protease, nuclease, kinase and phosphatase inhibitors to develop a multi-purpose preservative solution. Mentoring of the students expands their ability to plan, organize and design a biomedical research project.
Infrastructure Description: Not Applicable
Jobs Summary: 2 Wage Positions were created (Total jobs reported: 1)
Project Status: Completed
This award's data was last updated on Jun. 4, 2009. Help expand these official descriptions using the wiki below.
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