University of Wisconsin System
Grant: $376,728 - National Institutes of Health - Sep. 29, 2009
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Award Description: The aims of the parent grant, R01 GM068061, are to elucidate the structures of bacterial single-stranded (ss) DNA-binding proteins (SSBs) cooperatively bound to ssDNA, to reveal how enzymes take advantage of direct binding to SSB to process ssDNA/SSB substrates, and to characterize the anti-bacterial properties of inhibitors that block heterologous protein association with SSB. Significant progress on these goals now allow extension of the initial aims by (1) studying the universality of SSB/protein interaction strategies and (2) using Fluorescence Resonance Energy Transfer (FRET) to better define the structures of ssDNA/SSB complexes. This application requests funds to support hiring a research specialist and purchasing capital equipment (primarily US-made) that will improve the tempo of research for GM068061, both of which are outstanding investments for ARRA funds.
Project Description: See Award Description
Jobs Summary: The University of Wisconsin - Madison appreciates the American Recovery and Reinvestment Act (ARRA) funding. This additional funding will allow the University to retain employees and create new jobs. It is anticipated that the job classifications that will be created or retained for this award will be: Lead Researchers, Associate Researchers (including post doctoral research), Graduate Student Research Assistants, Undergraduate Student Research Assistants, Administrative Support positions, and/or Technical Support positions. (Total jobs reported: 0)
Project Status: Less Than 50% Completed
This award's data was last updated on Sep. 29, 2009. Help expand these official descriptions using the wiki below.
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