LA JOLLA, CA

SCRIPPS RESEARCH INSTITUTE, THE

Grant: $379,800 - National Institutes of Health - May. 22, 2009

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Award Description: The long-term scientific purpose the study is to develop risk-markers for individual susceptibility to alcoholism using brainwave measures. The proposal is derived from the PI's previous event-related brain potential (ERP) studies of familial alcoholism and central nervous system (CNS) function. However, alcohol consumption levels and tobacco smoking status both modulate CNS activity, although these factors are rarely been considered together. The study's main goal is to provide an empirical assessment of young adults who vary in their alcohol 'binge' drinking level, with genetic variability originating from familial-risk for alcoholism minimized. As ERPs also are sensitive to tobacco smoking status, subjects who have never smoked will be compared to individuals who smoke daily for each binge drinking level. Equal numbers of each gender will be assayed in each binge drinking and smoking group. The expected papers published from the study will clarify how CNS information processing is altered with alcohol ingestion in relationship to binge drinking amount, tobacco smoking history, and subject gender. Several pilot projects already have been completed, which are indicating the most sensitive paradigms that will be employed in the proposed major study.

Project Description: As defined in Award Description field.

Jobs Summary: The majority of the ARRA funding is being used to retain and increase the responsibilities of the previous graduate student who worked on the preliminary study. She is now a full-time Research Technician and manages the day-to-day aspects of the project that include subject running, data analysis, and organizational details. An additional part-time Research Technician was hired who is responsible for subject recruitment and assists in data collection. The PI also draws salary from the funding, oversees the scientific aspects of the study and meets daily with staff. The research participants are remunerated for their time, new equipment and supplies were purchased, and food was obtained for the sUbjects after the study to help decrease their alcohol level. (Total jobs reported: 3)

Project Status: Less Than 50% Completed

This award's data was last updated on May. 22, 2009. Help expand these official descriptions using the wiki below.


Funds Recipient

SCRIPPS RESEARCH INSTITUTE, THE
LA JOLLA, CA 92037
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Place of Performance

La Jolla, CA 92037
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