VIRGINIA COMMONWEALTH UNIVERSITY
Grant: $500,000 - National Institutes of Health - Sep. 30, 2009
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Award Description: The proposal 'Amphetamine acts as a Molecular Stent in the Dopamine Transporter' addresses the specific problem of amphetamine addiction, and introduces drugdevelopment strategies for detoxification of drug abusers. The central hypothesis rests on data suggesting that amphetamines become lodged in the dopamine transporter, which introduces a pathway for Na+ ions that persistently depolarize dopaminergic neurons, releasing dopamine inappropriately. Drug development relies on chemical similarities between amphetamine, which introduces a stent, and dopamine, which does not.
Project Description: Not Started
Jobs Summary: Not Started (Total jobs reported: 0)
Project Status: Not Started
This award's data was last updated on Sep. 30, 2009. Help expand these official descriptions using the wiki below.
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