SCRIPPS RESEARCH INSTITUTE, THE
Grant: $284,850 - National Institutes of Health - Jul. 17, 2009
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Award Description: The development of a safe and effective topical microbicide to prevent the sexual transmission of HIV could playa major role in worldwide reduction of the over 14,000 new HIV infections per day, and potentially save millions of lives. The goal of this project is to conduct in vitro and in vivo studies desgiend to support the preclinical development of short peptides as novel anti-HIV microbicides. In this project. we propose to fully characterize the anti-HIV efficacy of newly synthesized short amphipathic peptides in vitro as well as their toxicity and immunogenicity in vivo. If these studies unambiguously demonstrate that these peptides represent attractive anti-HIV microbicide candidates, they will then be tested as topical microbicides in vivo
Project Description: As defined in Award Description field.
Infrastructure Description: NONE
Jobs Summary: This award will accelerate the tempo of our scientific research and allow for job retention. Specifically the positions of one Research Associate and one Research Assistant (technician) will be retained and extended. Importantly, these two scientists have extensive expertise in HIV research and are thus indispensable for moving this project forward. (Total jobs reported: 2)
Project Status: Less Than 50% Completed
This award's data was last updated on Jul. 17, 2009. Help expand these official descriptions using the wiki below.
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