DURHAM, NC

Duke University

Grant: $722,081 - National Institutes of Health - Jun. 8, 2009

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Award Description: Abstract Recent increases in HIV diagnoses, sexually transmitted infections, and risk behavior indicate that research is needed to identify effective positive prevention interventions integrated within HIV primary care settings to reduce transmission risk behavior among HIV positive individuals. In particular, no effective interventions exist for those newly diagnosed. The time period after HIV diagnosis may be a #teachable moment# to motivate reductions in risk behavior or maintenance of lower risk. This is a window of opportunity, as the first year after receiving an HIV diagnosis may be a critical period for risk reduction, especially for men. The primary objective of this study is to evaluate the preliminary efficacy of a brief positive prevention intervention, based on the Information, Motivation and Behavioral Skills (IMB) Model, provided within the care and treatment of newly diagnosed HIV-positive men who have sex with men (MSM) to reduce transmission risk behavior. The proposed two-year study will randomly assign 120 sexually active, HIV-positive MSM, newly diagnosed within the prior 3 months, to receive either 1) comprehensive standard of care (CSC) or 2) Brief Risk Reduction + CSC (BRR), a brief individual intervention based on the IMB model that addresses sexual transmission risk behavior and substance use. BRR will follow the initial physician visit and integrate risk reduction in the context of personalized and relevant medical treatment to enhance the uptake of health-protective information. Assessments of information, motivational influences, behavioral skills, sexual risk behavior, and substance use will be collected at baseline, post-intervention (3-), and 6-, and 9- month follow-up points to determine intervention outcome effects. It is hypothesized that, relative to newly diagnosed HIV-positive men assigned to the comparison condition (CSC), those in the BRR intervention will exhibit significantly lower rates of HIV sexual transmission risk behavior, delayed onset to first unprotected sexual activity, and reduced substance use. Over time, reductions in transmission risk behaviors will be predicted by key elements of the IMB model and will demonstrate mediation of intervention effects. If successful, this research will identify a potentially efficacious brief positive prevention intervention that can be implemented in the care setting for newly HIV diagnosed men.

Project Description: See Award Description

Jobs Summary: Jobs created and retained in the following fields: FACULTY SCIENTIFIC/ELEC/RES TECHNOLOGY (Total jobs reported: 2)

Project Status: Less Than 50% Completed

This award's data was last updated on Jun. 8, 2009. Help expand these official descriptions using the wiki below.


Funds Recipient

Duke University
DUKE, NC 27708
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Place of Performance

2200 West Main Street, Suite 300
Durham, NC 27705
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Funds from this award have been disbursed to sub-grantees. Click here to see a list of sub-grantees.




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