UNIVERSITY OF CALIFORNIA, IRVINE
Grant: $298,666 - National Institutes of Health - Jul. 16, 2009
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Award Description: The use of nicotine via cigarette smoking forms lifelong memories that are recalled in response to environmental cues associated with previous nicotine use. This recall increases nicotine craving and is a factor for the continued use of nicotine. Memory formation requires long-lasting changes at synapses. This project will investigate how nicotine causes long-lasting changes at synapses in the hippocampus, a brain region associated with memory formation. This will help understand how the long-lasting memories are formed, which may aid in developing therapies for preventing the relapse, and thereby promote smoking cessation.
Project Description: The use of nicotine via cigarette smoking forms lifelong memories that are recalled in response to environmental cues associated with previous nicotine use. This recall increases nicotine craving and is a factor for the continued use of nicotine. Memory formation requires long-lasting changes at synapses. This project will investigate how nicotine causes long-lasting changes at synapses in the hippocampus, a brain region associated with memory formation. This will help understand how the long-lasting memories are formed, which may aid in developing therapies for preventing the relapse, and thereby promote smoking cessation.
Jobs Summary: Created: None Retained: None (Total jobs reported: 0)
Project Status: Less Than 50% Completed
This award's data was last updated on Jul. 16, 2009. Help expand these official descriptions using the wiki below.
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